OBSERVATION OF HYBRID CELLS OF MALIGNANT AND NORMAL CELLS INHIBITING INFILTRATING OF MALIGNANT PARENTS IN VITRO

Qi Yanchao

Department of Embryo, Henan Medical College, Henan Cancer Institute

Abstract: In this experiment, the infiltration ability of malignant human esophageal cancer cells (Eca-109) and the hybrid cells (109 × CHO) of the cells and normal Chinese hamster ovary cells (CHO) were studied by the method of co culture of myocardium and cells in vitro. The experiments showed that Eca-109 cells had the ability to infiltrate chicken embryo myocardium in vitro and had the behavior of destroying normal tissues; the hybrid cells of Eca-109 and CHO not only reduced their own infiltration ability, but also inhibited the infiltration ability of their malignant parent cell Eca-109; while the fusion cells of normal CHO cells did not affect the infiltration ability of malignant Eca-109 cells.

Key words:malignant cells;normal cells;hybridization;Inhibition;Infiltration;

• DOI：10.13705/j.issn.1671-6825.1985.02.004
• Album: Medical and Health Technology
• Special Topic: Oncology

Hybrid cell bodies of malignant and normal cells... Observation of inhibition of malignant parental cell infiltration_Qi Yan Chao. pdf