Clinical Sharing of Professor Qi in the Treatment of Pediatric Neurological Diseases

Professor Qi in the treatment of pediatric nerve deafness disease

Clinical Sharing

Regarding the question of whether deafness can be cured and when it can be achieved, we interviewed several domestic first-class otologists. Basically, they all said that they are still in the laboratory research stage and there is no substantial progress. The time from clinical application cannot be predicted. Ten years, decades, and hundreds of years are possible. Moreover, according to the current research route, when it can be applied, what can be treated is just deafness, "hair cells are not dead yet". For example, if a tree has just been blown down by the wind and roots, or has been drought, there is no way to do it now. In the future, there may be ways to rescue it, plant it again, or pour some water or medicine to make it "come back from the dead". However, for those who have been down for several years or decades, they are unable to recover.

Instead of waiting for a miracle, it is better to take scientific intervention and compensation measures as early as possible. Due to the emergence of stem cell theory and clinical practice in the past 10 years, this hopeless disease is being known by more and more people. Professor Qi has been treating neural stem cells for many years and has rich experience in neural stem cell science. There are countless patients treated by Professor Qi. Below we mainly introduce the cases of nerve deafness.

Nerve deafness refers to a disease in which the lesion is located in the hair cells of the spiral apparatus, the auditory nerve or the listening center at all levels, and the perception of sound and the conduction of nerve impulses are hindered, resulting in hearing loss and even hearing loss.

Clinical manifestations of hearing impairment, decline or even disappear as the main symptoms, patients often conscious ears cicadas or other sounds, in a quiet environment in patients feel more obvious. Can be accompanied by fever, headache, irritability, abdominal distension, waist acid fatigue and other systemic symptoms.

The range of hearing will become smaller and smaller, and the patient will be dull and sluggish because he cannot hear the outside sound.

● Time: 2012

● Location: Guangzhou

● Patient: Guo XX, male, 7 months old

● Prior to Professor Qi's consultation:

When the child was 2 and a half months old, the parents found that the child had no response to the surrounding noise and the call of the family, and knew that the problem was serious.

Immediately (2012-12-20) to the First Affiliated Hospital of Peking University, the 301 Hospital of the People's Liberation Army, the Navy General Hospital, etc., to find experts.

Results: 1. Brain MRI and CT results showed no abnormalities.

2.PDS gene sequence analysis showed no abnormality.

3.DPOAE audiology test failed on both sides.

Initial diagnosis: sensorineural deafness.

Treatment: Sodium bicarbonate ear drops, no special treatment.

It is recommended to review the hearing after three months.

At the moment, parents are anxious and seek medical treatment everywhere, which coincides with the introduction of friends (parents of Su XX) and uses our method.

After a course of treatment, the child's hearing basically returned to normal after two months.

The cause of deafness was found, and the symptomatic treatment relieved the symptoms. His parents were very happy. In order to prevent the recurrence of deafness, after Professor Qi's diagnosis and treatment, the second stage of recovery treatment was carried out, mainly for intramuscular injection of NGF, once a day, 2ML once a time. After the injection, Xiao Cute performed well.

After six months of rehabilitation, little cute, slowly normal growth. After that, the treatment will be changed to once a year. Two years later, basic health. But,

Stem cell infusion is not the only way to treat sensorineural deafness. The future treatment may be gene therapy, stem cell transplantation, drug therapy and cochlear implantation. Personalized combination therapy provides a broad prospect for hearing recovery of different types of sensorineural deafness.

The research of neural stem cells has gradually transited from the basic experimental stage to the clinical stage, especially the neural stem cells have certain clinical effect on the treatment of nerve repair and degenerative diseases. It is believed that the progress of these studies will gradually promote the understanding of human brain neurobiology and the development of clinical neuroscience. We 've been working on it.