Effect of Electroacupuncture on Monoamine Neurotransmitters in Brain Tissue of Young Rats with Cerebral Palsy

Liu ZhenhuanPan Pei GuangZhao YongQi Yanchao

Nanhai Obstetrics and Children's Hospital Affiliated to Guangzhou University of Chinese Medicine Nanhai Obstetrics and Children's Hospital Affiliated to Guangzhou University of Chinese Medicine Nanhai Obstetrics and Children's Hospital Affiliated to Guangzhou University of Chinese MedicineGuangzhou Cancer Hospital

Abstract: Objective To detect the content of monoamine neurotransmitters in hippocampus, cortex, basal nucleus and brainstem of cerebral palsy rats, observe the effect of acupuncture on them, and explore the mechanism of acupuncture in the treatment of cerebral palsy rats. Methods The model of cerebral palsy was prepared by the method of ischemia and hypoxia, the brain was decapitated after acupuncture treatment, the required brain areas were separated, and the content of monoamine neurotransmitters was detected by spectrophotometer. Results Compared with the sham-operated group, the contents of dopamine (DA) and 5-hydroxytryptamine (5-HT) in the basal nucleus and norepinephrine (NE) in the brainstem decreased significantly (P<0.05), and the contents of dopamine (DA) and 5-hydroxytryptamine (5-HT) in the basal nucleus and norepinephrine (NE) in the brainstem increased significantly after acupuncture treatment (P<0.05). Conclusion It is suggested that increasing the monoamine neurotransmitter content in the relevant brain regions may be one of the possible mechanisms of acupuncture in the treatment of cerebral palsy in young rats.

Key words:Acupuncture;Cerebral palsy;Monoamine neurotransmitters;

Conference Name: 2007 Academic Annual Meeting of Guangdong Rehabilitation Medicine Association and Health Research Committee of Guangdong Social Society

Meeting time: 2007-11

Venue: Guangzhou, Guangdong, China

• Album: Medical and Health Technology
• Topic: Traditional Chinese Medicine
• Classification number: R245

Effect of Electroacupuncture on Monoamine Neurotransmitters in Brain Tissue of Cerebral Palsy Rats